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Tuesday, 23 September 2014

PhD Position in Bioinformatic Analysis of Astrocyte Function @ VIB Center for the Biology of Disease, K.U.Leuven

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The Laboratory of Glia Biology is looking for an enthusiastic PhD student to join the team by the beginning or middle of 2015.

Background:
To date, the majority of CNS studies have focused on understanding the function of neurons – which are traditionally viewed as the computational units of the brain. However, the vast majority of cells in the mammalian CNS are actually astrocytes. It is now becoming increasingly obvious that astrocytes are involved in all aspects of CNS function, from initial formation of synapses through to the active modulation of information transfer at these structures. Therefore, breakdown in astrocyte function is inevitably involved in both acute and chronic neurological conditions, such as stroke and cancer.

VIB Department of Plant Systems Biology

The project:

  • Our group believes that astrocyte function is best understood by taking a ‘bottom-up’ approach, in which function is set by the transcriptional status of individual cells, or distinct subpopulations of cells, in the brain. Functional analysis of our own astrocyte expression data, supplemented by integration of publically available data sets, will yield astrocyte (subtype) specific networks, that will lead to a better understanding of (differential) astrocyte function in both the healthy and diseased CNS (with a particular emphasis on cancer).

Profile

​Candidates must have, or expect to obtain, a first class honors degree (or equivalent) in bioinformatics or a related subject. A strong interest in neuroscience is required.

We offer

  1. The project will be conducted in the lab of Matthew Holt. The group has a strong international track record in studying the molecular basis of CNS function. The scientific excellence of the group was recently recognized with a prestigious ERC grant. As a result, we expect to offer a renewable contract, a competitive salary and benefits (although candidates will also be expected to apply for their own external funding).
  2. The VIB Center for the Biology of Disease is an international research department with a strong emphasis on neuroscience. Researchers have access to high-end technologies (including a state-of-the-art sequencing core) and technical support in a new, purpose-built research institute. Translational research is encouraged by close proximity to the University Clinic.
  3. A good knowledge of English is sufficient for all communications, both within and outside the institute. Situated in the heart of Europe (close to Brussels and with excellent transport links), the position is ideally suited to international candidates.

How to apply?

Motivated and interactive individuals, with a strong interest in applying viral vectors to neuroscience questions, are advised to apply online.
Please add the contact details of 2 referees in the appropriate field of the online application form.

Apply Online

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Monday, 22 September 2014

Senior Research Fellow @ Indian Agricultural Statistics Research Institute Library Avenue, Pusa, New Delhi

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Walk-in-interview will be held on September 30, 2014 at 11:00 A.M. at IASRI, New Delhi for a project “Whole Genome based SNP mining and Development of Breed Signatures for Dairy and Dual-purpose indigenous Cattle” funded by Department of Biotechnology, Ministry of Science and Technology, Government of India, New Delhi for the following posts. The appointment will be on contractual basis up to July, 2017 or till the termination of the project whichever is earlier and the incumbent shall not have any claim for regular appointment under ICAR.

Emoluments for Senior Research Fellow: Consolidated Rs: 14000/- per month + 30% HRA (OM No A.20020/11/97-IFD dated March, 2010)

Age Limit :The Upper age limit for SRFs will be as under:

  1. 35 years for men
  2. 40 years for women
  • Interested candidates are requested to appear for Walk-in-Interview on the date and time as specified above in Room No. 106, Training Cum Administrative Block of the Institute along with their application giving bio-data with attested copies of certificates, degrees, testimonials, etc. and one passport size photograph. ORIGINAL CERTIFICATES/ DEGREES are needed to be produced at the time of interview. No T.A. /D.A. will be paid for appearing in the interview.

Terms and Conditions

  1. Interested candidates fulfilling the above qualifications are invited to appear for Walk-In interview at Indian Agricultural Statistics Research Institute, Library Avenue, Pusa, New Delhi -110012 with application, Bio-Data, all educational and experience certificates.
  2. Candidates are necessarily required to produce ORIGINAL CERTIFICATES at the time of interview, which after verification will be returned to them.
  3. The selected candidates shall not claim any regular appointment as the position is purely temporary.
  4. No TA/ DA will be paid for appaearing in interview.
  5. Decision of Director, IASRI will be final and binding in all respects
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The 3rd call of the TECNIOSPRING fellowship programme co-financed by the EU through the Marie Curie Actions and the Catalan Government.

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Postdoctoral position in multi-scale systems biology at GRIB (IMIM-UPF)
The candidate will contribute to the development of a multi-scale modeling framework aiming to predict cellular function from genotype by combining models with high-throughput data sets. The methodology will follow an integrative strategy based on the hierarchical decomposition of biological systems into their constitutive modular parts such as at molecular, cell, network, tissue, organism, and population. Duties will involve the development of algorithms and protocols for modeling genotype/phenotype relationships in drug design, with a focus on overcoming toxicity and resistance mechanisms through multi-scale systems biology approaches. This project is oriented towards technology transfer and will be carried out through ongoing collaboration with biotech and pharma companies.

¡Bienvenidos a la Pompeu Fabra!: Welcome to the Pompeu Fabra !

We seek candidates to apply for a senior postdoctoral position at the Research Programme on Biomedical Informatics (GRIB) in the 3rd call of the TECNIOSPRING fellowship programme co-financed by the EU through the Marie Curie Actions and the Catalan Government.

Qualifications

  • The successful candidate will have a Ph.D. in computer science, engineering, chemical or biological sciences. Essential qualifications include good programming skills and experience with biological model simulation. Additional skills include experience with bioinformatics or chemoinformatics demonstrated though publications, strong collaborative skills and ability to work and communicate in a team environment is also required.
  • Candidates should have at least four years of postdoctoral experience or eight years of equivalent experience, including one year experience in applied research or technology transfer and some experience in the scientific management of other researchers, both in a research centre or a private company. This call is open to all nationalities and aims to attract research taIent from abroad so it is mandatory that candidates should not have worked or lived in Spain for more than twelve months in a two years period before the call.
The successful applicant will have a two year contract with an annual gross salary of 44.000 Euros and full social security coverage. She/he will work in a stimulating and multidisciplinary scientific environment and will receive training in the field of technology transfer and in a wide range of soft skills related to project management, dissemination, etc…The job position complies with theCharter and Code for the Recruitment of Researchers.

Bioinformatics studies cancer from a genomic point of view

About the GRIB

The Research Programme on Biomedical Informatics (GRIB) is a joint research programme of IMIM-Hospital del Mar Research Institute and Universitat Pompeu Fabra (UPF) located in Barcelona (Spain). We carry out fundamental research and technological developments on the application of advanced information technologies and computational methods in health and life sciences. GRIB has a wide experience in the participation and coordination of international research projects and a long tradition of collaborations with the pharmaceutical and biotechnological industry.

How to apply:

Interested applicants should submit a motivation letter describing relevant experience, an updated CV and contact information for at least two referees toPablo Carbonell, pablo.carbonell@upf.edu.
Application deadline is October 15th, 2014.

More information about the TECNIOSRPING call at

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Sunday, 21 September 2014

Post Doc In Bioinformatics @ The Seungchan Kim lab (Biocomputing Lab),TGen

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The post-doc will develop and implement computational algorithms and a system to study computationally derived gene regulatory networks, in conjunction with existing public database of signaling pathways such as Pathway Commons. The post-doc will also assist in developing grant proposals, based on the outcomes of aforementioned research, in addition to publishing research results.
In addition, the post-doc will co-mentor students (high school, undergraduate and/or graduate students) in related research.

Translational Genomics Research Institute (TGen)

The Seungchan Kim lab (Biocomputing Lab) at TGen focuses on development and application of computational methods to analyze high throughput genomic and transcriptomic data.

Our research incorporates statistical and computational tools to study cancer biology, focusing on:

    1. identification of biomarkers and/or therapeutic targets for cancers,
    2. molecular classification of cancers, and
    3. understanding and mathematical modeling of genetic regulatory networks, with the special focus on contextual genomic regulation.

Detailed Description

  1. Develop a system to archive computationally derived gene regulatory networks (cGRNs) from public data such as TCGA and ICGC.
  2. Develop algorithms to analyze archived cGRNs.
  3. Develop algorithms to identify condition-specific GRN.
  4. Mentor students (high school, undergraduate and/or graduate students) in related research
  5. Collaborate with other scientists within and outside the institute.

Job Requirements

  1. Ph.D. in bioinformatics, computational biology, or computer science with experience related field of research.
  2. Strong programming skills  C/C++ or Java.
  3. Experience with public genomic database such as TCGA is required.
  4. Experience in database system, especially noSQL, is desired.

Read more/Apply online:

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Saturday, 20 September 2014

Research Associate & Junior Research Fellow @ CSIR - UNIT FOR RESEARCH AND DEVELOPMENT OF INFORMATION PRODUCTS,Pune

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Opportunity for young Bioinformatics Professionals to make a career in the area of Intellectual Property
CSIR has set up a Unit for Research and Development of Information Products (CSIR-URDIP) at Pune to work in the area of scientific informatics. One of the major focus areas of research work at CSIR-URDIP is PATENT INFORMATICS. With the increasing applications of Bioinformatics in the areas of life sciences industry such as Agriculture and Health Care (Diagnostics and Drugs), the output of research in these area is being protected by different forms of Intellectual Property rights. Realizing the importance of IP in the Bioinformatics field, Department of Biotechnology (DBT) has sanctioned a project on “Development, Facilitation and Harvesting of Bioinformatics related Intellectual Property” at CSIR-URDIP.
  • The project will involve application of Patent Informatics tools and techniques to Bioinformatics (including creation of patent landscapes, preparation of techno-legal reports of patentability, freedom to operate studies) to help protect IPRs and develop and conduct training programmes on IPRs related to Bioinformatics.
CSIR-URDIP invites applications from young Bioinformatics professionals to work on this emerging area which offers challenging opportunities and attractive career possibilities in future.

Position I: Research Associate

  • No of Positions: One
  • Consolidated amount Payable: Rs. 22,000/- per month + 20% HRA= Rs.26,400

Qualification:

PhD in Bioinformatics. In exceptional cases, candidature of M. Tech. candidates with First class in Bioinformatics with three years of relevant work experience will also be considered.

Job requirement:

  • The prospective candidate will be expected to identify patents/scientific literature in field of Bioinformatics, evaluate them Vis a Vis other patents in fields and come up landscape/FTO/Patentability reports.

Desirable qualifications and Skills

  1. Knowledge of Patent law as evidenced by Post Graduate Diploma in Intellectual Property / Patent Law from recognized Institution / university or passed Indian patent agent examination
  2. Aptitude for analysis of research publications and patent documents, data mining and analytical skills  Excellent Oral and Written Communication in English language
  3. Proficiency in use of commonly used software for word processing, database searching, spreadsheet, presentations

Age Limit:

  • 35 years. The age should not exceed the limit indicated as on a closing date of receipt of completed application form.
  • Upper age limit is relaxable for 5 years for SC/ST, OBC, Physically handicapped and female candidates as per CSIR/Government of India rules.

Position II: Junior Research Fellow

  • No of Positions: one
  • Consolidated amount Payable: Rs. 16,000/- + 20% HRA = 19,200

Qualification:

M.Sc / BE or equivalent in Bioinformatics with minimum of 55% marks in aggregate
  • Job requirement: Scientific literature and patent search, analysis and Report Writing

Preference:

  • Preference will be given to candidates with knowledge of patents and or 1-2 years of experience + Knowledge of Computers (MS Excel + Word Processing)

Age Limit:

  • 28 years. The age should not exceed the limit indicated as on a closing date of receipt of completed application form.
  • Upper age limit is relaxable for 5 years for SC/ST, OBC, Physically handicapped and female candidates as per CSIR/Government of India rules.
  • The engagement for both the positions will be made initially for a period of six months, which may be extended or curtailed depending on the satisfactory performance and conduct of the candidates. The engagement will be purely on temporary and contract basis and shall not be a CSIR/URDIP/DBT appointment, temporary or otherwise and shall not entitle him/her to any right/claim, implicit or explicit, for his/her consideration against any CSIR/URDIP /DBT post/fellowship.
For details please visit our website (www.urdip.res.in/careers) for further details and apply online by 30th September, 2014.

Read more/Apply Online

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2 PhD student positions in Bioinformatics @ The Department for Applied Bioinformatics,Goethe University Frankfurt

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Project: The source of genomic innovation in the human pathogen Acinetobacter baumannii
Employment: Contract duration is 36 months.
Wanted: We are looking for two talented and highly motivated students that enjoy working in a team.
Project outline: Taking the lead in the arms race against their host’s immune system is characteristic for all successful pathogens. The multi-drug resistant Acinetobacter baumannii strains have proven increasingly successful in coping with this challenge. Preliminary results indicate that this success is tightly linked to A. baumannii’s high genetic flexibility both with respect to modifying existing information and with respect to mining its environment for novel genetic information. The DFG research group 2251/1 “Adaptation and persistence of the emerging pathogen A. baumannii” is dedicated to address the precise nature underlyingA. baumannii pathogenicity from different starting point.

Students about the Goethe - University Frankfurt

  • Our project represents the bioinformatics backbone of the research group and has two main objectives. In a broader evolutionary analysis, we will assess the role of natural competence for the acquisition of A. baumannii pathogenicity related factors and for general bacterial evolution. Software development for establishing function-aware phylogenetic profiles of large protein sets will be a central work package. In a complementary approach, we will use comparative genomics to identify the genetic basis of A. baumanniivirulence. To this end, we will complement publicly available genome sequences of A. baumannii with in-house determined sequences of selected clinical strains. We will then trace the evolutionary origins of virulence factors in a phylogenomic network of bacterial diversity. The results from both objectives will then be integrated in a web-accessible database that distributes information to all project partners.
General information: The successful candidates will be supported by the DFG Research Group 2251/1 Adaptation and persistence of the emerging pathogen Acinetobacter baumannii(http://www.bio.uni-frankfurt.de/51172482). The PhD student will be trained in state-of-the art bioinformatics methods of evolutionary sequence analysis and comparative genomics. Complementary competence will be acquired by joint projects with the biological and medical project partners within the research group.

Eligibility:

  • Applicants must fulfill the eligibility criteria for participating in a German PhD program.
  • Researchers can be nationals of any country within or outside of the EU.
  • Good knowledge of the English language (fluently speaking and writing) is essential.

Requirements:

  • We expect very good programming skills in at least one of the following programming/scripting languages: Java, Perl, Python, C, C++, or R. Experience in the handling and analysis of high-throughput sequence data in an functional and evolutionary framework is highly desired. For at least one candidate excellent knowledge in the set-up and maintenance of relational databases is required.
Application: Please send your application in electronic format to Prof. Dr. Ingo Ebersberger (neumaier@bio.uni-frankfurt.de), Goethe University, Institute for Cell Biology and Neuroscience, Dept. for Applied Bioinformatics, Max-von-Laue Strasse 13, 60438 Frankfurt am Main. Applications will be accepted until the position is filled. Earliest starting date is October 2014. Please include the following documents into your application:
  1. CV
  2. Copies of all university degree(s) and school certificates (if possible, including university Grade Point Average scores)
  3. A letter of motivation (1 page) outlining your qualification for the project
  4. Two letters of reference
  5. A list of publications (if available)
  • The Goethe University advocates equality of opportunity for men and women and therefore expressly encourages women to apply. Persons with severe disabilities will be given preferential consideration in case of equal qualifications.

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Thursday, 18 September 2014

PhD scholarship in Protein and Proteomics @ the department of Systems Biology, Technical University of Denmark (DTU)

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PhD scholarship in Protein and Proteomics Studies of Proteolytic Degradation of Pig Bristle by Microbial Consortia
A PhD position is available with the Enzyme and Protein Chemistry group at the department of Systems Biology, Technical University of Denmark (DTU) in the project “Keratin2Protein: Novel approach to protein recovery from slaughterhouse waste through microbial conversion”. The research is conducted in collaboration with Department of Biology, University of Copenhagen, the Section for Sustainable Biotechnology, Aalborg University and Danish industry partners.

Come to DTU

You can read more about Enzyme and Protein Chemistry at

http://www.bio.dtu.dk/english/Research/Research-groups/Enzyme-and-Protein-Chemistry


Responsibilities and tasks

  • The potential to convert biological residual resources into new alternative high value products is especially important in Denmark and Europe due to serious protein deficit. The project aims at significant protein food chain gain and production of high value products through waste utilization. 
  • The PhD candidate will focus on keratin degrading systems to discover and characterise proteolytic reactions conferred by microbial consortia at the protein and proteome level by using advanced mass spectrometry techniques as well as production and characterisation of recombinant target proteases.
  • The successful candidate is a talented highly motivated and self-driven person who enjoys working with different techniques and disciplines in an international environment and in collaboration with industry. Fluency in English and good communication skills are required.

Qualifications


  • Candidates should have a master's degree in engineering or a similar degree with an academic level equivalent to the master's degree in engineering.

Approval and Enrolment

The scholarships for the PhD degree are subject to academic approval, and the candidates will be enrolled in one of the general degree programmes of DTU. For information about the general requirements for enrolment and the general planning of the scholarship studies, please see the DTU PhD Guide.

Assessment

  • The assessment of the applicants will be made by Prof. Birte Svensson assisted by project collaboration partners.

We offer

We offer an interesting and challenging job in an international environment focusing on education, research, public-sector consultancy and innovation, which contribute to enhancing the economy and improving social welfare. We strive for academic excellence, collegial respect and freedom tempered by responsibility. The Technical University of Denmark (DTU) is a leading technical university in northern Europe and benchmarks with the best universities in the world.

Salary and appointment terms

The salary and appointment terms are consistent with the current rules for PhD degree students. The period of employment is 3 years.

Further information

Further information may be obtained from Professor Birte Svensson, +45 4525 2740, bis@bio.dtu.dk or Associate Professor Per Hägglund, +45 4525 5503, ph@bio.dtu.dk
Please do not send applications to this e-mail address, instead apply online as described below.
You can read more about the Department of Systems Biology on www.bio.dtu.dk

Application

  • Please submit your online application no later than 8 October 2014.
  • Applications must be submitted as one pdf file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one pdf file. The file must include:
  1. A letter motivating the application (cover letter)
  2. Curriculum vitae
  3. Grade transcripts and BSc/MSc diploma
  4. Excel sheet with translation of grades to the Danish grading system (see guidelines and excel spreadsheet here)
Candidates may apply prior to obtaining their master's degree, but cannot begin before having received it.
All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.
  • Department of Systems Biology represents a large concentration of academic biotechnological research in Denmark, including protein and enzyme chemistry, food biochemistry, bioinformatics, systems biology, molecular biology, fermentation technology, physiology and genetics of industrial microorganisms and medical microbiology. The department hosts senior and junior faculty members and post-doctoral fellows, PhD students and technical/administrative personnel, around 260 in total. In addition to bachelor, master and PhD education, collaborative research and innovation together with national and international universities and industries is given high priority at the department.
  • DTU is a technical university providing internationally leading research, education, innovation and public service. Our staff of 5,700 advance science and technology to create innovative solutions that meet the demands of society; and our 10,000 students are educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government, and public agencies.

Read more

http://www.bio.dtu.dk

Apply Online

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Research Associate - DST-PURSE program @ Bioinformatics Centre,Savitribai Phule Pune University

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Savitribai Phule Pune University, one of the premier universities in India, is positioned in the North-western part of Pune city. It occupies an area of about 411 acres. It was established on 10th February, 1949 under the Poona University Act. The university houses 46 academic departments. It is popularly known as the 'Oxford of the East'. It has about 307 recognized research institutes and 612 affiliated colleges offering graduate and under-graduate courses.
The university attracts many foreign students due to its excellent facilities. It offers good accommodation facility. There is a provision of hostel for the students. There is a well-stocked library containing plenty of books regarding various subjects. The university offers different scholarships to the students. The university conducts seminars and conferences for the students.

Job  details:

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PhD Fellowship in Bioinformatics and Evolutionary Genomics @ Institut de Biotecnologia i de Biomedicina (IBB) of the Universitat Autònoma de Barcelona (UAB)

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PhD Fellowship in Bioinformatics and Evolutionary Genomics
A FPI fellowship to carry out a PhD degree in Bioinformatics and Evolutionary Genomics is available at the Bioinformatics of Genomic Diversity and the Comparative and Functional Genomics groups located at the Institut de Biotecnologia i de Biomedicina (IBB) of the Universitat Autònoma de Barcelona (UAB). The successful candidate will join a young, dynamic, and interdisciplinary team and will collaborate in the research of the group within the project “Understanding genome variation from nucleotides to phenotypes in Drosophila and humans”, funded by the Ministerio de Economía y Competitividad.
  • In particular, the PhD project will be focused on the development of models to estimate the action of selection on genome variation, including both SNPs and structural variants, especially inversions, and the integration of population genomics data with functional data to characterize the genomic determinants of evolution.

Requirements:

We are looking for motived individuals with high interest in science and a Master degree in an area related to Bioinformatics, Evolution, Genomics or Genetics.

Conditions:

  • Total duration of contract will be of 4 years with an annual salary of 16.422 €.

Application:

To express interest in the position, send an e-mail with a copy of your CV and contact information to Antonio Barbadilla (antonio.barbadilla@uab.cat) and Mario Cáceres (mcaceres@icrea.cat).
Official application should be done through the MINECO website:

Application deadline:

Please send expression of interest before September 21st 2014. Official application should be completed on September 26th 2014.

Additional information:

  1. Genomics, Bioinformatics and Evolutionary Biology group:
  2. Comparative and Functional Genomics group:

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